个人简介：李盼，博士，河南大学有机化学学科“黄河学者”特聘教授。本科、硕士毕业于河南大学（2005-2012）；博士毕业于中科院兰州化学物理研究所（2012-2015）；南佛罗里达大学博士后（2016-2018）；2018.08入职河南大学，2020.06晋升教授，2023年9月担任有机学位点负责人。近年来在Nat. Commun. Org. Lett. Chem. Commun.等国际期刊上发30余篇SCI论文，H因子20，引用1000余次。受邀担任Org. Lett.; Chem. Commun.; J. Org. Chem.; Chinese J. Catal.等学术期刊审稿人。
讲授课程：有机化学
研究方向：(1)重氮化合物的自由基/卡宾反应性；（2）张力环开环官能团化；（3）高价碘化学
课题组简介：课题组成立于2019年9月，主要围绕自由基、卡宾等有机活性中间体开展研究，发展新策略、新方法、新反应，通过键的精准断裂与可控重组，高效、绿色的构建功能化的杂环类药物分子。欢迎对科研有兴趣且勤奋的本科生加入610实验室。
课题组主页：http://www.x-mol.com/groups/li_pan
ORCID: http://orcid.org/0000-0001-6658-9207
邮箱：panli@iin3d.com
成果及论文：
Independence in HENU
2023年
(36) Keyong Zhu, Wen-Jing Yu, Xinlong Zhou, Chaogui Xu, Guanzhen Zhao, Yun Chai,* Shi-Jun Li,* Yuanqing Xu and Pan Li*. Base-Free Regio- and Stereoselective Photochemical Synthesis of Enol Ethers from 1,3-Dicarbonyl Compounds. Chem. Commun. 2023, 59, 12605–12608.
(35) Shichong Wang, Huayan Xu, Ruoyu Zhang, Siyu Zhang, Yun Chai*, Bingchuan Yang*, Jingjing Zhao*, Yuanqing Xu, and Pan Li*. Regioselective Synthesis of N-Vinyl Pyrazoles from Vinyl Sulfonium Salts with Diazo Compounds. Org. Lett. 2023, 25, 6746–6750. Highlighted by ChemBeanGo.
(34) Mengting Cao, Yikun Ren, Ruoyu Zhang, Huayan Xu, Pengfei Cheng*, Hao Xu*, Yuanqing Xu, and Pan Li*. Photochemical “Cut and Sew” Transformations of Ethynylbenziodoxolone Reagents and Diazo Compounds. Org. Lett. 2023, 25, 6300–6304. Highlighted by ChemBeanGo.
(33) Keyong Zhu, Xinlong Zhou, Yikun Ren, Linhui Dong, Guanzhen Zhao, Jingjing Zhao* and Pan Li*. Visible Light-Induced Carbene Reactivity of Acceptor Diazoalkanes: Deconstructive Difunctionalizations of Cyclic Ethers with Nucleophiles. Chem Commun. 2023, 59, 631–634.
2022年
(32) Jiupeng Liu, Shuo Tang, Huayan Xu, Ruoyu Zhang, Jingjing Zhao*, Puyu Zhang*, and Pan Li*. Photocatalytic Regioselective [2 + 2 + 1] Radical Annulation of Alkenes with tert-Butyl Nitrite and gem-Dihalides. Org. Lett. 2022, 24, 9366–9369. Highlighted by ChemBeanGo.
(31) Yantao Liu, Keyong Zhu, Jingjing Zhao*, and Pan Li*. Photocatalytic Regioselective Difunctionalization of Alkenes with Diazo Compounds and tert-Butyl Nitrite: Access to γ-Oximino Esters. Org. Lett. 2022, 24, 6834-6838. Highlighted by ChemBeanGo.
(30) Jiaqi Li, Shichong Wang, Jingjing Zhao*, and Pan Li*. Visible Light-Promoted Radical-Mediated Ring-Opening/Cyclization of Vinyl Benzotriazoles: An Alternative Approach to Phenanthridines. Org. Lett. 2022, 24, 5977–5981. Highlighted by ChemBeanGo.
(29) Keyong Zhu, Mengting Cao, Guanzhen Zhao, Jingjing Zhao,* and Pan Li*. Visible Light-Promoted Diazoacetates and Nitriles Generating Nitrilium Ions Trapped by Benzotriazoles and Carboxylic Acids. Org. Lett. 2022, 24, 5855–5859. Highlighted by ChemBeanGo.
(28) Tao Zhang, Shichong Wang, Dandan Zuo, Jingjing Zhao,* Wen Luo,* Chaojie Wang, and Pan Li*. Palladium-Catalyzed Carbonylative [5 + 1] Cycloaddition of N-Tosyl Vinylaziridines: Solvent Controlled Divergent Synthesis α,β- and β,γ-Unsaturated δ-Lactams. J. Org. Chem. 2022, 87, 10408–10415.
(27) Jiupeng Liu, Shuo Tang, Shichong Wang, Mengting Cao, Jingjing Zhao*, Puyu Zhang*, and Pan Li*. Visible-Light-Induced 1,6-Enynes Triggered C–Br Bond Homolysis of Bromomalonates: Solvent-Controlled Divergent Synthesis of Carbonylated and Hydroxylated Benzofurans. J. Org. Chem. 2022, 87, 9250–9258.
(26) Dandan Zuo, Tao Zhang, Jingjing Zhao*, Wen Luo*, Chaojie Wang, and Pan Li*. Palladium-Catalyzed Regioselective [5 + 1] Annulation of Vinyl Aziridines/Epoxides with ClCF2COONa. Org. Lett. 2022, 24, 4630−4634. Highlighted by Organic Chemistry Portal.
2021年
(25) Jiupeng Liu, Shuo Tang, Mengyao Zhao, Jianing Huai, Jingya Yu, Jingjing Zhao,* and Pan Li*. The Reactivity of Vinyl Epoxides/Oxetanes/Cyclopropanes toward Arynes: Access to Functionalized Phenanthrenes. ACS Omega 2021, 6, 35852−35865.
(24) Yantao Liu, Keyong Zhu, Yuting Kong, Xiao Li, Jie Cui, Yifan Xia, Jingjing Zhao,* Shaofeng Duan, Pan Li*. Merging Gold/Copper Catalysis and Copper/Photoredox Catalysis: An Approach to Alkyl Oxazoles from N-Propargylamides. J. Org. Chem. 2021, 86, 18247–18256. Highlighted by Organic Chemistry Portal.
(23) Jiupeng Liu, Jiaqi Li, Bowen Ren, Yun Zhang, Linyi Xue, Yanying Wang, Jingjing Zhao,* Puyu Zhang,* Xuejun Xu, and Pan Li*. Domino Ring-Opening of N-Tosyl Vinylaziridines Triggered by Aryne Diels–Alder Reaction. Adv. Synth. Catal. 2021, 363, 4734–4739.
(22) Yantao Liu, Yating Shi, Lanen Wei, Ke Zhao, Jingjing Zhao*, Puyu Zhang, Xuejun Xu, Pan Li*. Gold-Catalyzed One-Pot Synthesis of Polyfluoroalkylated Oxazoles from N-Propargylamides Under Visible-Light Irradiation. Chem. Asian J. 2021, 16, 2417–2420. (Invited for Special Issue: Metals in Functional Materials and Catalysis: Fundamentals and Critical Applications. Highlighted by WileyChem and ChemBeanGo.)
(22) Pan Li, Jingjing Zhao, Feng Shi. Dipolar Cycloaddition Reactions in “Modern Aryne Chemistry”. Chapter 3, Editor: A. T. Biju; Wiley-VCH. 2021, ISBN: 978-3-527-34646-2, pages 69–110.
2020年
(20) Yantao Liu, Wen Luo*, Zhenjie Wang, Yuxin Zhao, Jingjing Zhao*, Xuejun Xu, Chaojie Wang, Pan Li*. Visible-Light Photoredox-Catalyzed Formal [5+1] Cycloaddition of N‑Tosyl Vinylaziridines with Difluoroalkyl Halides. Org. Lett. 2020, 22, 9658–9664. (Highlighted by Synfacts, ChemBeanGo and Organic Chemistry Portal. Featured in Org. Chem. Highlights: Heteroaromatics.)
2019年
(19) Jingjing Zhao, Pan Li*, Yaohua Xu, Yixin Shi, Fuwei Li*. Nickel-Catalyzed Transformation of Diazoacetates to Alkyl Radicals Using Alcohol as a Hydrogen Source. Org. Lett. 2019, 21, 9386–9390. (Highlighted by Organic Chemistry Portal.)
Prior to HENU
(18) Pan Li, Jingjing, Zhao, Lijun Shi, Jin Wang, Xiaodong Shi*, Fuwei Li*. Iodine Catalyzed Diazo Activation to Access Radical Reactivity. Nat. Commun. 2018, 9, 1972.
(17) Pan Li, Jingjing, Zhao, Xinjian Li, Fuwei Li*. Alkali-induced Ring-Opening of 2-Amidodihydrofuran and Manganese Catalyzed Aerobic Dehydrogenation Annulation: An Access to Functionalized Oxazole. J. Org. Chem. 2017, 82, 4569–4577.
(16) Jingjing, Zhao, Pan Li (coworker), Xinjian Li, Chungu Xia, Fuwei Li*. Straightforward Synthesis of Functionalized Chroman-4-ones through Cascade Radical Cyclization-Coupling of 2-(Allyloxy)arylaldehydes. Chem. Commun. 2016, 52, 3661–3664.
(15) Pan Li, Jingjing, Zhao, Chungu Xia, Fuwei Li*. The Development of Carbene-Stabilized N–O Radical Coupling Strategy in Metal-Free Regioselective C–H Azidation of Quinolone N-Oxides. Org. Chem. Front. 2015, 2, 1313–1317.
(14) Pan Li, Jingjing, Zhao, Chungu Xia, Fuwei Li*. Direct Oxidative Coupling of Enamides and 1,3-Dicarbonyl Compounds: A Facile and Versatile Approach to Dihydrofurans, Furans, Pyrroles and Dicarbonyl Enamides. Org. Lett. 2014, 16, 5992–5995.
(13) Pan Li, Jingjing, Zhao, Rui Lang, Chungu Xia, Fuwei Li*. Copper-Catalyzed Methyl Esterification of Aromatic Aldehydes and Benzoic Alcohols by TBHP as both Oxidant and Methyl Source. Tetrahedron Lett. 2014, 55, 390–393.
(12) Pan Li, Chunrui Wu, Jingjing, Zhao, Yang Li, Weichao Xue, Richard C. Larock, Feng Shi*. One-Pot Synthesis of Dihydrobenzisoxazoles from Hydroxylamines, Acetylenedicarboxylates, and Arynes via in Situ Generation of Nitrones. Can. J. Chem. 2013, 91, 42–49.
(11) Pan Li, Chunrui Wu, Jingjing, Zhao, Donald C. Rogness, Feng Shi*. Synthesis of Substituted 1H-Indazoles from Arynes and Hydrazones. J. Org. Chem. 2012, 77, 3149–3158. (Highlighted by Synfacts and Organic Chemistry Portal.)
(10) Pan Li, Jingjing, Zhao, Chunrui Wu, Richard C. Larock, Feng Shi*. Synthesis of 3-Substituted Indazoles from Arynes and N-Tosylhydrazones. Org. Lett. 2011, 13, 3340–3343. Highlighted by Organic Chemistry Portal.
(9) Jingjing, Zhao, Pan Li, Chungu Xia, Fuwei Li*. Facile Synthesis of Trisubstituted Carbazoles by Acid-Catalyzed Ring-Opening Annulation of 2-Amidodihydrofurans with Indoles. Chem. Eur. J. 2015, 21, 16383–16386. Highlighted by Synfacts.
(8) Jingjing, Zhao, Pan Li, Chungu Xia, Fuwei Li*. Metal-Free Regioselective C-3 Nitration of Quinolone N-Oxides with Tert-Butyl Nitrite. RSC Adv. 2015, 5, 32835–32838.
(7) Jingjing, Zhao, Pan Li, Chungu Xia, Fuwei Li*. Direct N-Acylation of Azoles via a Metal-Free Catalyzed Oxidative Cross-Coupling Strategy. Chem. Commun. 2014, 50, 4751–4754. Top 25 most-read ChemComm articles in Q1, 2014.
(6) Jingjing Zhao, Pan Li, Chunrui Wu, Hongli Chen, Wenying Ai, Renhong Sun, Richard C. Larock, Feng Shi*. Aryne [3+2] Cycloaddition with N-Sulfonylpyridinium Imides and in Situ Generated N-Sulfonylisoquinolinium Imides: a Potential Route to Pyrido[1,2-b] Indazoles and Indazolo[3,2-a]isoquinolines. Org. Biomol. Chem. 2012, 10, 1922–1930.
(5) Jingjing Zhao, Chunrui Wu, Pan Li, Wenying Ai, Hongli Chen, Chaojie Wang, Richard C. Larock, Feng Shi*. Synthesis of Pyrido[1,2-b]indazoles via Aryne [3+2] Cycloaddition with N-Tosylpyridinium Imides. J. Org. Chem. 2011, 76, 6837–6843. Highlighted by Synfacts.
(4) Qi Xing, Pan Li, Hui, Lv, Rui, Lang, Chungu Xia, Fuwei Li. Acid-catalyzed Acylation Reaction via C–C Bond Cleavage: A Facile and Mechanistically Defined Approach to Synthesize 3-Acylindoles. Chem. Commun. 2014, 50, 12181–12184.
(3) Chunrui Wu, Pan Li, Jingjing, Zhao, Weichao Xue, Yang Li, Feng Shi. Pd-Catalyzed Oxidative Coupling of Monosubstituted Sydnones and Terminal Alkynes. Tetrahedron Lett. 2011, 52, 3797–3801.
(2) Xinjian Li, Qi Xing, Pan Li, Jingjing, Zhao, Fuwei Li. Three-Component Povarov Reaction with Alcohols as Alkene Precursors: Efficient Access to 2-Arylquinolines. Eur. J. Org. Chem. 2017, 618–625.
(1) Chunrui Wu, Qingbo Wang, Jingjing, Zhao, Pan Li, Feng Shi. Cycloaddition of N-Sulfonylpyridinium Imides and Isoquinolinium Imides with Acetylenedicarboxylates: A Practical Synthesis of Pyrazolo[1,5-a]pyridine and Pyrazolo[5,1-a]isoquinoline Derivatives. Synthesis, 2012, 44, 3033–3042.
授权专利
（1） 李盼，赵静静，张涛 一种钯催化条件下合成α,β-不饱和杂环己基酮类化合物的方法，专利号：2022106219905， 公告号：CN 114853664 B
（2） 李盼，赵静静，朱柯勇 一种光催化条件下合成亚胺基苯并三唑化合物的方法，专利号：2022106220885 公告号：CN114835652B
（3） 赵静静，李盼，刘艳涛 光催化条件下合成肟类化合物的方法 专利号：2022104261113 公告号：CN 114621115 B
